• Appropriate Time for Test-of-Cure when Diagnosing Gonorrhoea with a Nucleic Acid Amplification Test 

      Hjelmevoll, Stig Ove; Olsen, Merethe Elise; Sollid, Johanna U Ericson; Haaheim, Håkon; Melby, Kjetil K.; Moi, Harald; Unemo, Magnus; Skogen, Vegard (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
    • Candida auris 

      Sollid, Johanna U Ericson (Chapter; Bokkapittel, 2019)
      Candida auris (C. auris) er en gjærsopp som kan forårsake alvorlige infeksjoner hos mennesker. Infeksjoner med Candida auris forekommer i hovedsak i helseinstitusjoner og rammer som regel alvorlig syke pasienter. I tillegg er behandling vanskelig fordi soppen ofte er resistent/motstandsdyktig mot de vanligste medikamentene som brukes ved Candida-infeksjon.
    • Chitosan-Based Nanomedicine to Fight Genital Candida Infections: Chitosomes 

      Andersen, Toril; Mishchenko, Ekaterina; Flaten, Gøril Eide; Sollid, Johanna U Ericson; Mattsson, Sofia; Tho, Ingunn; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-04)
      Vaginal infections are associated with high recurrence, which is often due to a lack of efficient treatment of complex vaginal infections comprised of several types of pathogens, especially fungi and bacteria. Chitosan, a mucoadhesive polymer with known antifungal effect, could offer a great improvement in vaginal therapy; the chitosan-based nanosystem could both provide antifungal effects and ...
    • Circulating sex-steroids and Staphylococcus aureus nasal carriage in a general female population 

      Stensen, Dina Benedicte Berg; Småbrekke, Lars; Olsen, Karina; Grimnes, Guri; Nielsen, Christopher Sivert; Sollid, Johanna U Ericson; Simonsen, Gunnar Skov; Almås, Bjørg; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02)
      <p>Objective: <i>Staphylococcus aureus</i> is a major human pathogen, and nasal carriers have an increased risk for infection and disease. The exploration of host determinants for nasal carriage is relevant to decrease infection burden. Former studies demonstrate lower carriage prevalence in women and among users of progestin-only contraceptives. The aim of this study was to investigate the possible ...
    • Coagulase-negative staphylococci in southern brazil: Looking toward its high diversity 

      de Oliveira, Caio Fernando; Cavanagh, Jorunn Pauline; Fredheim, Elizabeth G Aarag; Reiter, Keli Cristine; Rieger, Alexandre; Klingenberg, Claus; D'Azevedo, Pedro Alves; Sollid, Johanna U Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05)
      Introduction: Coagulase-negative staphylococci (CoNS) are the most prevalent pathogens in nosocomial infections and may serve as a reservoir of mobile genetic elements such as the staphylococcal cassette chromosome mec (SCCmec) encoding methicillin resistance. Molecular characterization of SCCmec types combined with advanced molecular typing techniques may provide essential information for ...
    • Core genome conservation of Staphylococcus haemolyticus limits sequence based population structure analysis 

      Cavanagh, Jorunn Pauline; Klingenberg, Claus Andreas; Hanssen, Anne-Merethe; Aarag, Elizabeth; Francois, Patrice; Schrenzel, Jaques; Flægstad, Trond; Sollid, Johanna U Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The notoriously multi-resistant Staphylococcus haemolyticus is an emerging pathogen causing serious infections in immunocompromised patients. Defining the population structure is important to detect outbreaks and spread of antimicrobial resistant clones. Currently, the standard typing technique is pulsed-field gel electrophoresis (PFGE). In this study we describe novel molecular typing schemes for ...
    • Culturing periprosthetic tissue in BacT/Alert® Virtuo blood culture system leads to improved and faster detection of prosthetic joint infections 

      Sanabria-Moreno, Adriana Maria; Røkeberg, Merethe E.O.; Johannessen, Mona; Sollid, Johanna U Ericson; Simonsen, Gunnar Skov; Hanssen, Anne Merethe (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-10)
      <i>Background</i> - Blood culture bottles (BCBs) provide a semiautomated method for culturing periprosthetic tissue specimens. A study evaluating BCBs for culturing clinical samples other than body fluids is needed before implementation into clinical practice. Our objective was to evaluate use of the BacT/Alert® Virtuo blood culture system for culturing periprosthetic tissue specimens. <p> ...
    • Genetic variability in the sdrD gene in Staphylococcus aureus from healthy nasal carriers 

      Ajayi, Clement; Åberg, Espen; Askarian, Fatemeh; Sollid, Johanna U Ericson; Johannessen, Mona; Hanssen, Anne Merethe (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-16)
      <p><i>Background</i>: <i>Staphylococcus aureus</i> cell wall anchored Serine Aspartate repeat containing protein D (<i>sdrD</i>) is a member of the microbial surface component recognising adhesive matrix molecules (MSCRAMMs). It is involved in the bacterial adhesion and virulence. However the extent of genetic variation in <i>S. aureus sdrD</i> gene within isolates from healthy carriers are not ...
    • Host and microbe determinants that may influence the success of S. aureus colonization 

      Johannessen, Mona; Sollid, Johanna U Ericson; Hanssen, Anne-Merethe (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Staphylococcus aureus may cause serious skin and soft tissue infections, deep abscesses, endocarditis, osteomyelitis, pneumonia, and sepsis. S. aureus persistently colonizes 25–30% of the adult human population, and S. aureus carriers have an increased risk for infections caused by the bacterium. The major site of colonization is the nose, i.e., the vestibulum nasi, which is covered with ordinary ...
    • Localization of Staphylococcus aureus in tissue from the nasal vestibule in healthy carriers 

      Hanssen, Anne-Merethe; Kindlund, Bert; Stenklev, Niels Christian; Furberg, Anne-Sofie; Fismen, Silje; Olsen, Renate Slind; Johannessen, Mona; Sollid, Johanna U Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-05)
      <p><b>Background:</b> Colonization of the body is an important step in Staphylococcus aureus infection. S. aureus colonizes skin and mucous membranes in humans and several animal species. One important ecological niche of S. aureus is the anterior nares. More than 60% of the S. aureus in the nose are found in vestibulum nasi. Our aim was to describe the localization of S. aureus in nasal tissue ...
    • Prevalence and population structure of Staphylococcus aureus nasal carriage in healthcare workers in a general population. The Tromsø Staph and Skin Study 

      Olsen, Karina; Sangvik, Maria; Simonsen, Gunnar Skov; Sollid, Johanna U Ericson; Sundsfjord, Arnfinn; Thune, Inger; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Healthcare workers (HCWs) may be a reservoir for Staphylococcus aureus transmission to patients. We examined whether HCW status is associated with S. aureus nasal carriage and population structure (spa types) in 1302 women (334 HCWs) and 977 men (71 HCWs) aged 30–69 years participating in the population-based Tromsø Study in 2007–2008. Multivariable logistic regression models were used. While no ...
    • Shotgun-Metagenomics on Positive Blood Culture Bottles Inoculated With Prosthetic Joint Tissue: A Proof of Concept Study 

      Sanabria-Moreno, Adriana Maria; Hjerde, Erik; Johannessen, Mona; Sollid, Johanna U Ericson; Simonsen, Gunnar Skov; Hanssen, Anne Merethe (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-17)
      Clinical metagenomics is actively moving from research to clinical laboratories. It has the potential to change the microbial diagnosis of infectious diseases, especially when detection and identification of pathogens can be challenging, such as in prosthetic joint infection (PJI). The application of metagenomic sequencing to periprosthetic joint tissue (PJT) specimens is often challenged by low ...
    • Staphylococcus aureus nasal carriage is associated with serum 25-hydroxyvitamin D levels, gender and smoking status. The Tromso Staph and Skin Study 

      Olsen, Karina; Falch, Birgit Margrethe; Danielsen, Kjersti; Johannessen, Mona; Sollid, Johanna U Ericson; Thune, Inger; Grimnes, Guri; Jorde, Rolf; Simonsen, Gunnar Skov; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Vitamin D induces the expression of antimicrobial peptides with activity against Staphylococcus aureus. Thus, we studied the association between serum 25-hydroxyvitamin D (25(OH)D) and S. aureus nasal colonization and carriage. Nasal swabs, blood samples and clinical data from 2,115 women and 1,674 men, aged 30–87 years, were collected in the Tromsø Staph and Skin Study 2007–08, as part of the ...
    • Staphylococcus aureus nasal carriage is associated with serum 25-hydroxyvitamin D levels, gender and smoking status. The Tromsø Staph and Skin Study 

      Olsen, Karina; Falch, Birgit Margrethe; Danielsen, Kjersti; Johannessen, Mona; Sollid, Johanna U Ericson; Thune, Inger; Grimnes, Guri; Jorde, Rolf; Simonsen, Gunnar Skov; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Vitamin D induces the expression of antimicrobial peptides with activity against Staphylococcus aureus. Thus, we studied the association between serum 25-hydroxyvitamin D (25(OH)D) and S. aureus nasal colonization and carriage. Nasal swabs, blood samples and clinical data from 2,115 women and 1,674 men, aged 30–87 years, were collected in the Tromsø Staph and Skin Study 2007–08, as part of the ...
    • A staphylococcus aureus TIR domain protein virulence factor blocks TLR2-mediated NF-κB signaling 

      Askarian, Fatemeh; van Sorge, Nina; Sangvik, Maria; Beasley, Federico C; Henriksen, Jørn Remi; Sollid, Johanna U Ericson; van Strijp, Jos A. G.; Nizet, Victor; Johannessen, Mona (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Vibrio vulnificus 

      Sollid, Johanna U Ericson (Chapter; Bokkapittel, 2019)
      <i>Vibrio vulnificus</i> er en bakterie som trives i saltvann over 20 grader og som kan gi sykdom hos personer med sår eller nedsatt immunforsvar (såkalt opportunistisk infeksjon). Alvorlige sykdom forekommer oftest nær Taiwan, Sør-Korea, Japan og i Mexicogolfen. I senere år er det rapportert flere tilfeller med alvorlige infeksjon med <i>Vibrio vulnificus</i> hos personer som har badet i nordiske ...
    • Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus heamolyticus in European hopsitals 

      Cavanagh, Jorunn Pauline; Hjerde, Erik; Holden, Matthew T.G.; Kahlke, Tim; Klingenberg, Claus; Flægstad, Trond; Parkhill, J; Bentley, Stephen D; Sollid, Johanna U Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)